The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zn(2)-C6 fungal-type DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22: Upc2p

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
11 Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q12151 (/IDA) Q12151 (/IDA) Q12151 (/IDA)
(1 more)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
11 Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q12151 (/IDA) Q12151 (/IDA) Q12151 (/IDA)
(1 more)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
11 Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q12151 (/IMP) Q12151 (/IMP) Q12151 (/IMP)
(1 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
7 Q05958 (/HDA) Q05958 (/HDA) Q05958 (/HDA) Q05958 (/HDA) Q05958 (/HDA) Q05958 (/HDA) Q05958 (/HDA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter GO:0035961
Any process that activates or increases the frequency, rate or extent of ergosterol biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
11 Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q12151 (/IMP) Q12151 (/IMP) Q12151 (/IMP)
(1 more)
Positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter GO:1904741
A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation.
11 Q05958 (/IGI) Q05958 (/IGI) Q05958 (/IGI) Q05958 (/IGI) Q05958 (/IGI) Q05958 (/IGI) Q05958 (/IGI) Q12151 (/IGI) Q12151 (/IGI) Q12151 (/IGI)
(1 more)
Positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter GO:1904741
A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation.
11 Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q05958 (/IMP) Q12151 (/IMP) Q12151 (/IMP) Q12151 (/IMP)
(1 more)
Positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter GO:0035969
Any process that activates or increases the frequency, rate or extent of sterol import by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
7 Q05958 (/IGI) Q05958 (/IGI) Q05958 (/IGI) Q05958 (/IGI) Q05958 (/IGI) Q05958 (/IGI) Q05958 (/IGI)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
6 Q12151 (/IMP) Q12151 (/IMP) Q12151 (/IMP) Q12151 (/IMP) Q6FX18 (/IMP) Q6FX18 (/IMP)
Positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter GO:0035969
Any process that activates or increases the frequency, rate or extent of sterol import by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 Q12151 (/IMP) Q12151 (/IMP) Q12151 (/IMP) Q12151 (/IMP)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
4 Q12151 (/IMP) Q12151 (/IMP) Q12151 (/IMP) Q12151 (/IMP)
Ergosterol biosynthetic process GO:0006696
The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.
2 Q6FX18 (/IMP) Q6FX18 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 Q6FX18 (/IMP) Q6FX18 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
11 Q05958 (/IC) Q05958 (/IC) Q05958 (/IC) Q05958 (/IC) Q05958 (/IC) Q05958 (/IC) Q05958 (/IC) Q12151 (/IC) Q12151 (/IC) Q12151 (/IC)
(1 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
11 Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q12151 (/IDA) Q12151 (/IDA) Q12151 (/IDA)
(1 more)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
11 Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q05958 (/IDA) Q12151 (/IDA) Q12151 (/IDA) Q12151 (/IDA)
(1 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q12151 (/HDA) Q12151 (/HDA) Q12151 (/HDA) Q12151 (/HDA)