The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phytochelatin synthase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Glutathione gamma-glutamylcysteinyltransferase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutathione gamma-glutamylcysteinyltransferase activity GO:0016756
Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.
7 A5JYS0 (/IDA) A5JYS1 (/IDA) Q10075 (/IDA) Q9S7Z3 (/IDA) Q9S7Z3 (/IDA) Q9ZWB7 (/IDA) Q9ZWB7 (/IDA)
Glutathione gamma-glutamylcysteinyltransferase activity GO:0016756
Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.
3 Q10075 (/IMP) Q9S7Z3 (/IMP) Q9S7Z3 (/IMP)
Cadmium ion binding GO:0046870
Interacting selectively and non-covalently with cadmium (Cd) ions.
3 Q10075 (/IDA) Q9S7Z3 (/IDA) Q9S7Z3 (/IDA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 Q9S7Z3 (/IDA) Q9S7Z3 (/IDA)
ATPase-coupled arsenite transmembrane transporter activity GO:0015446
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out).
2 Q9S7Z3 (/IDA) Q9S7Z3 (/IDA)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phytochelatin biosynthetic process GO:0046938
The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
5 A5JYS0 (/IDA) A5JYS1 (/IDA) Q10075 (/IDA) Q9ZWB7 (/IDA) Q9ZWB7 (/IDA)
Phytochelatin biosynthetic process GO:0046938
The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
5 A5JYS0 (/IMP) A5JYS1 (/IMP) Q10075 (/IMP) Q9S7Z3 (/IMP) Q9S7Z3 (/IMP)
Detoxification of copper ion GO:0010273
Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
3 A5JYS0 (/IMP) A5JYS1 (/IMP) Q10075 (/IMP)
Detoxification of copper ion GO:0010273
Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
2 A5JYS0 (/IGI) A5JYS1 (/IGI)
Arsenite transport GO:0015700
The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q9S7Z3 (/IDA) Q9S7Z3 (/IDA)
Indole glucosinolate catabolic process GO:0042344
The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.
2 Q9S7Z3 (/IMP) Q9S7Z3 (/IMP)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
2 Q9S7Z3 (/IMP) Q9S7Z3 (/IMP)
Response to arsenic-containing substance GO:0046685
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
2 Q9S7Z3 (/IDA) Q9S7Z3 (/IDA)
Response to arsenic-containing substance GO:0046685
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
2 Q9S7Z3 (/IMP) Q9S7Z3 (/IMP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9S7Z3 (/IDA) Q9S7Z3 (/IDA)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9S7Z3 (/IMP) Q9S7Z3 (/IMP)
Detoxification of mercury ion GO:0050787
Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg
2 A5JYS0 (/IGI) A5JYS1 (/IGI)
Defense response by callose deposition in cell wall GO:0052544
Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
2 Q9S7Z3 (/IMP) Q9S7Z3 (/IMP)
Detoxification of cadmium ion GO:0071585
Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.
2 A5JYS0 (/IGI) A5JYS1 (/IGI)
Detoxification of cadmium ion GO:0071585
Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.
2 A5JYS0 (/IMP) A5JYS1 (/IMP)
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 Q10075 (/IMP)
Cellular detoxification of cadmium ion GO:0098849
Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.
1 Q10075 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q9S7Z3 (/IDA) Q9S7Z3 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q10075 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q10075 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q10075 (/HDA)