The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Probable Ufm1-specific protease 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thiolester hydrolase activity GO:0016790
Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.
7 Q2M1D1 (/ISS) Q3B8N0 (/ISS) Q5RCS9 (/ISS) Q5XIB4 (/ISS) Q5ZIF3 (/ISS) Q7T347 (/ISS) Q9VUR0 (/ISS)
UFM1 hydrolase activity GO:0071567
Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates.
7 Q2M1D1 (/ISS) Q3B8N0 (/ISS) Q5RCS9 (/ISS) Q5XIB4 (/ISS) Q5ZIF3 (/ISS) Q7T347 (/ISS) Q9VUR0 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q9NUQ7 (/IPI) Q9NUQ7 (/IPI) Q9NUQ7 (/IPI) Q9NUQ7 (/IPI) Q9NUQ7 (/IPI)
Thiolester hydrolase activity GO:0016790
Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.
5 Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP)
UFM1 hydrolase activity GO:0071567
Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates.
5 Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP)
Thiolester hydrolase activity GO:0016790
Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.
1 Q99K23 (/IDA)
Thiolester hydrolase activity GO:0016790
Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.
1 Q99K23 (/ISO)
UFM1 hydrolase activity GO:0071567
Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates.
1 Q99K23 (/IDA)
UFM1 hydrolase activity GO:0071567
Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates.
1 Q99K23 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
7 Q2M1D1 (/ISS) Q3B8N0 (/ISS) Q5RCS9 (/ISS) Q5XIB4 (/ISS) Q5ZIF3 (/ISS) Q7T347 (/ISS) Q9VUR0 (/ISS)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
5 Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP)
Regulation of intracellular estrogen receptor signaling pathway GO:0033146
Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
5 Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP) Q9NUQ7 (/IMP)
Regulation of intracellular estrogen receptor signaling pathway GO:0033146
Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
3 Q5RCS9 (/ISS) Q5XIB4 (/ISS) Q99K23 (/ISS)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
1 Q99K23 (/ISO)
Regulation of intracellular estrogen receptor signaling pathway GO:0033146
Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
1 Q99K23 (/ISO)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
1 Q94218 (/IGI)
Positive regulation of chemotaxis GO:0050921
Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
1 Q94218 (/IMP)
Protein localization to non-motile cilium GO:0097499
A process in which a protein is transported to, or maintained in, a location within a non-motile cilium.
1 Q94218 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 Q3B8N0 (/ISS) Q5RCS9 (/ISS) Q5XIB4 (/ISS) Q5ZIF3 (/ISS) Q7T347 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 Q3B8N0 (/ISS) Q5RCS9 (/ISS) Q5XIB4 (/ISS) Q5ZIF3 (/ISS) Q7T347 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
10 Q3B8N0 (/ISS) Q5RCS9 (/ISS) Q5XIB4 (/ISS) Q5ZIF3 (/ISS) Q7T347 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS) Q9NUQ7 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q580A1 (/IDA) Q99K23 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q99K23 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q99K23 (/IDA)
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
1 Q9VUR0 (/HDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q94218 (/IDA)