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CATH Superfamily 3.90.650.10

PurM-like C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
PurM-like C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Phosphoribosylformylglycinamidine synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphoribosylformylglycinamidine synthase activity GO:0004642
Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.
 15 Q48LX3 (/ISS) Q48LX3 (/ISS) Q48LX3 (/ISS) Q83DR5 (/ISS) Q886W6 (/ISS) Q886W6 (/ISS) Q886W6 (/ISS) Q8EC57 (/ISS) Q9KTN2 (/ISS) Q9KTN2 (/ISS)
(5 more)
Phosphoribosylformylglycinamidine synthase activity GO:0004642
Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.
 11 P15254 (/IMP) P15254 (/IMP) P15254 (/IMP) P15254 (/IMP) P15254 (/IMP) P15254 (/IMP) P15254 (/IMP) P15254 (/IMP) P38972 (/IMP) P38972 (/IMP)
(1 more)
Phosphoribosylformylglycinamidine synthase activity GO:0004642
Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.
 8 P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
 8 P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA)
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
 8 P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA)
Phosphoribosylformylglycinamidine synthase activity GO:0004642
Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.
 2 Q5AUA9 (/RCA) Q5AUA9 (/RCA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
 15 Q48LX3 (/ISS) Q48LX3 (/ISS) Q48LX3 (/ISS) Q83DR5 (/ISS) Q886W6 (/ISS) Q886W6 (/ISS) Q886W6 (/ISS) Q8EC57 (/ISS) Q9KTN2 (/ISS) Q9KTN2 (/ISS)
(5 more)
'de novo' IMP biosynthetic process GO:0006189
The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.
 11 P15254 (/IC) P15254 (/IC) P15254 (/IC) P15254 (/IC) P15254 (/IC) P15254 (/IC) P15254 (/IC) P15254 (/IC) P38972 (/IC) P38972 (/IC)
(1 more)
Glutamine metabolic process GO:0006541
The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
 8 P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA)
Purine nucleotide biosynthetic process GO:0006164
The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
 3 P38972 (/IMP) P38972 (/IMP) P38972 (/IMP)
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
 2 Q5AUA9 (/RCA) Q5AUA9 (/RCA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 8 P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 8 P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 3 P38972 (/HDA) P38972 (/HDA) P38972 (/HDA)