The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphoribosylglycinamide synthetase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphoribosylamine--glycine ligase. [EC: 6.3.4.13]
ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)- (5-phospho-D-ribosyl)glycinamide.
  • Formerly EC 6.3.1.3.
272 A0A024L855 A0A045HU98 A0A059HPH3 A0A070SKI8 A0A072ZAW4 A0A075WKG2 A0A083ZPS1 A0A0A7T2D1 A0A0A8F4H1 A0A0B6V577
(262 more...)
Phosphoribosylformylglycinamidine cyclo-ligase. [EC: 6.3.3.1]
ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.
    17 A0A0L8VR11 A0A1D8NPD9 A6ZTV6 B3LHS7 G2WDM5 N1P3F9 P00967 P07244 P16340 P20772
    (7 more...)
    Phosphoribosylglycinamide formyltransferase. [EC: 2.1.2.2]
    10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
      7 P00967 P16340 P21872 P22102 Q26255 Q59A32 Q64737