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CATH Superfamily 3.90.550.10

Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 76: Beta-1,4 N-acetylgalactosaminyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase. [EC: 2.4.1.92]
UDP-N-acetyl-alpha-D-galactosamine + O-(N-acetyl-alpha-neuraminyl)- (2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl-(1<->1)- ceramide = UDP + O-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl- (1->4)-O-(N-acetyl-alpha-neuraminyl-(2->3))-O-beta-D-galactopyranosyl- (1->4)-beta-D-glucopyranosyl-(1<->1)-ceramide.
  • Catalyzes the formation of the gangliosides (i.e. sialic-acid- containing glycosphingolipids) GM2, GD2 and SM2 from GM3, GD3 and SM3, respectively.
  • Asialo-GM3 and lactosylceramide are also substrates, but glycoproteins and oligosaccharides are not substrates.
 6 Q00973 Q09200 Q09200 Q10468 Q3UN35 Q3UN35