The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"SMAD MH1 domain
".
FunFam 6: Mothers against decapentaplegic homolog
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity GO:0030617
A TGF-beta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators.
|
1 | Q5U110 (/IGI) |
|
BMP receptor binding GO:0070700
Interacting selectively and non-covalently with a BMP receptor.
|
1 | Q5U110 (/IPI) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Malpighian tubule morphogenesis GO:0007443
The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Anterior/posterior pattern specification, imaginal disc GO:0007448
The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Histoblast morphogenesis GO:0007488
The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Morphogenesis of larval imaginal disc epithelium GO:0016335
The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Eye-antennal disc development GO:0035214
Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Negative regulation of synaptic growth at neuromuscular junction GO:0045886
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Negative regulation of muscle organ development GO:0048635
Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Cell elongation involved in imaginal disc-derived wing morphogenesis GO:0090254
The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis.
|
3 | O15968 (/IMP) Q5U110 (/IMP) Q8SZT4 (/IMP) |
|
Negative regulation of SMAD protein complex assembly GO:0010991
Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.
|
1 | Q5U110 (/IDA) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | Q5U110 (/IDA) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | Q5U110 (/IGI) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | Q5U110 (/IMP) |
|
Negative regulation of pathway-restricted SMAD protein phosphorylation GO:0060394
Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
|
1 | Q5U110 (/IDA) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.