The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
4'-phosphopantetheinyl transferase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Holo-(Acyl carrier protein) synthase 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Holo-[acyl-carrier-protein] synthase activity GO:0008897
Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
24 P37623 (/IDA) P37623 (/IDA) P37623 (/IDA) P37623 (/IDA) P37623 (/IDA) P37623 (/IDA) P37623 (/IDA) P37623 (/IDA) P37623 (/IDA) P37623 (/IDA)
(14 more)
Holo-[acyl-carrier-protein] synthase activity GO:0008897
Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
24 P37623 (/IMP) P37623 (/IMP) P37623 (/IMP) P37623 (/IMP) P37623 (/IMP) P37623 (/IMP) P37623 (/IMP) P37623 (/IMP) P37623 (/IMP) P37623 (/IMP)
(14 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
24 P37623 (/IGI) P37623 (/IGI) P37623 (/IGI) P37623 (/IGI) P37623 (/IGI) P37623 (/IGI) P37623 (/IGI) P37623 (/IGI) P37623 (/IGI) P37623 (/IGI)
(14 more)
Peptidyl-serine phosphopantetheinylation GO:0018070
The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine.
24 P37623 (/NAS) P37623 (/NAS) P37623 (/NAS) P37623 (/NAS) P37623 (/NAS) P37623 (/NAS) P37623 (/NAS) P37623 (/NAS) P37623 (/NAS) P37623 (/NAS)
(14 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.