The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Histone acetyl transferase 1 (HAT1), N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Histone acetyltransferase type B catalytic subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
H4 histone acetyltransferase activity GO:0010485
Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
12 O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA)
(2 more)
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
11 O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
11 O14929 (/IPI) O14929 (/IPI) O14929 (/IPI) O14929 (/IPI) O14929 (/IPI) O14929 (/IPI) O14929 (/IPI) O14929 (/IPI) O14929 (/IPI) O14929 (/IPI)
(1 more)
H4 histone acetyltransferase activity GO:0010485
Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
2 Q5M939 (/ISS) Q8BY71 (/ISS)
H4 histone acetyltransferase activity GO:0010485
Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
1 Q8BY71 (/ISO)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA packaging GO:0006323
Any process in which DNA and associated proteins are formed into a compact, orderly structure.
11 O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS)
(1 more)
DNA replication-dependent nucleosome assembly GO:0006335
The formation of nucleosomes on newly replicated DNA, coupled to strand elongation.
11 O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA)
(1 more)
DNA replication-independent nucleosome assembly GO:0006336
The formation of nucleosomes outside the context of DNA replication.
11 O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA)
(1 more)
Internal protein amino acid acetylation GO:0006475
The addition of an acetyl group to a non-terminal amino acid in a protein.
11 O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS)
(1 more)
Histone H4 acetylation GO:0043967
The modification of histone H4 by the addition of an acetyl group.
11 O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA)
(1 more)
Histone H4 acetylation GO:0043967
The modification of histone H4 by the addition of an acetyl group.
2 Q5M939 (/ISS) Q8BY71 (/ISS)
DNA replication-dependent nucleosome assembly GO:0006335
The formation of nucleosomes on newly replicated DNA, coupled to strand elongation.
1 Q8BY71 (/ISO)
DNA replication-independent nucleosome assembly GO:0006336
The formation of nucleosomes outside the context of DNA replication.
1 Q8BY71 (/ISO)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
1 Q5M939 (/IEP)
CENP-A containing nucleosome assembly GO:0034080
The formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
1 Q0KIB3 (/IMP)
Histone H4 acetylation GO:0043967
The modification of histone H4 by the addition of an acetyl group.
1 Q8BY71 (/ISO)
Positive regulation of innate immune response GO:0045089
Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 Q0KIB3 (/HMP)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 Q0KIB3 (/HMP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
11 O14929 (/HDA) O14929 (/HDA) O14929 (/HDA) O14929 (/HDA) O14929 (/HDA) O14929 (/HDA) O14929 (/HDA) O14929 (/HDA) O14929 (/HDA) O14929 (/HDA)
(1 more)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
11 O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA)
(1 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
11 O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS)
(1 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
11 O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA)
(1 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
11 O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS) O14929 (/TAS)
(1 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
11 O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA)
(1 more)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
11 O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA) O14929 (/IDA)
(1 more)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 Q8BY71 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q8BY71 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q8BY71 (/ISO)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 Q8BY71 (/ISO)