The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"UDP-galactose 4-epimerase, domain 1
".
FunFam 2: GDP-L-fucose synthase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 14 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GDP-L-fucose synthase activity GO:0050577
Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+.
|
22 |
G5EER4 (/IDA)
O49213 (/IDA)
P32055 (/IDA)
P32055 (/IDA)
P32055 (/IDA)
P32055 (/IDA)
P32055 (/IDA)
P32055 (/IDA)
P32055 (/IDA)
P32055 (/IDA)
(12 more) |
|
Oxidoreductase activity GO:0016491
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
|
5 | Q74FI1 (/ISS) Q74FI1 (/ISS) Q93N55 (/ISS) Q93N55 (/ISS) Q93N55 (/ISS) |
|
Racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857
Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule.
|
5 | Q74FI1 (/ISS) Q74FI1 (/ISS) Q93N55 (/ISS) Q93N55 (/ISS) Q93N55 (/ISS) |
|
Electron transfer activity GO:0009055
Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
|
2 | Q13630 (/TAS) Q13630 (/TAS) |
|
GDP-4-dehydro-D-rhamnose reductase activity GO:0042356
Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed.
|
2 | Q13630 (/TAS) Q13630 (/TAS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q13630 (/IPI) Q13630 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | P23591 (/ISO) P23591 (/ISO) |
|
GDP-mannose 3,5-epimerase activity GO:0047918
Catalysis of the reaction: GDP-mannose = GDP-L-galactose.
|
2 | Q13630 (/IDA) Q13630 (/IDA) |
|
GDP-mannose 3,5-epimerase activity GO:0047918
Catalysis of the reaction: GDP-mannose = GDP-L-galactose.
|
2 | P23591 (/ISO) P23591 (/ISO) |
|
GDP-mannose 3,5-epimerase activity GO:0047918
Catalysis of the reaction: GDP-mannose = GDP-L-galactose.
|
2 | Q9W1X8 (/ISS) Q9W1X8 (/ISS) |
|
GDP-L-fucose synthase activity GO:0050577
Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+.
|
2 | P23591 (/ISO) P23591 (/ISO) |
|
Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
|
1 | G4WJD3 (/IDA) |
|
GDP-4-dehydro-D-rhamnose reductase activity GO:0042356
Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed.
|
1 | Q382D8 (/ISA) |
|
GDP-L-fucose synthase activity GO:0050577
Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+.
|
1 | Q609T0 (/ISS) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Colanic acid biosynthetic process GO:0009242
The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide.
|
4 | Q609T0 (/ISS) Q93N55 (/ISS) Q93N55 (/ISS) Q93N55 (/ISS) |
|
GDP-L-fucose biosynthetic process GO:0042350
The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.
|
3 | G5EER4 (/IDA) Q9W1X8 (/IDA) Q9W1X8 (/IDA) |
|
'de novo' GDP-L-fucose biosynthetic process GO:0042351
The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).
|
3 | Q13630 (/IDA) Q13630 (/IDA) Q382D8 (/IDA) |
|
T cell mediated cytotoxicity GO:0001913
The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
|
2 | P23591 (/IMP) P23591 (/IMP) |
|
Leukocyte cell-cell adhesion GO:0007159
The attachment of a leukocyte to another cell via adhesion molecules.
|
2 | Q13630 (/NAS) Q13630 (/NAS) |
|
Lipopolysaccharide biosynthetic process GO:0009103
The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.
|
2 | Q74FI1 (/ISS) Q74FI1 (/ISS) |
|
GDP-mannose metabolic process GO:0019673
The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
|
2 | Q13630 (/IDA) Q13630 (/IDA) |
|
GDP-mannose metabolic process GO:0019673
The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
|
2 | P23591 (/ISO) P23591 (/ISO) |
|
DsRNA transport GO:0033227
The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9W1X8 (/IMP) Q9W1X8 (/IMP) |
|
'de novo' GDP-L-fucose biosynthetic process GO:0042351
The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).
|
2 | P23591 (/ISO) P23591 (/ISO) |
|
'de novo' GDP-L-fucose biosynthetic process GO:0042351
The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).
|
2 | Q13630 (/TAS) Q13630 (/TAS) |
|
L-fucose biosynthetic process GO:0006005
The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose).
|
1 | O49213 (/IDA) |
|
'de novo' GDP-L-fucose biosynthetic process GO:0042351
The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).
|
1 | Q382D8 (/ISA) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q13630 (/TAS) Q13630 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | Q13630 (/HDA) Q13630 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q382D8 (/IDA) |
|
Kinetoplast GO:0020023
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
|
1 | Q382D8 (/IDA) |