View in Gene3D

CATH Superfamily 3.90.230.10

Creatinase/methionine aminopeptidase superfamily

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Creatinase/methionine aminopeptidase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2: Xaa-Pro aminopeptidase 3

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Xaa-Pro aminopeptidase. [EC: 3.4.11.9]
Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.
  • Generally membrane bound enzyme present in both mammalian and bacterial cells.
  • Belongs to peptidase family M24B.
 174 A0A069CHT5 A0A069CHT5 A0A069CHT5 A0A069CHT5 A0A069CHT5 A0A069CHT5 A0A069CHT5 A0A069CHT5 A0A069CHT5 A0A069CHT5
(164 more...)
Xaa-Pro dipeptidase. [EC: 3.4.13.9]
Hydrolysis of Xaa-|-Pro dipeptides. Also acts on aminoacyl-hydroxyproline analogs. No action on Pro-|-Pro.
  • Possibly thiol dependent.
  • Cytosolic from most animal tissues.
  • Belongs to peptidase family M24A.
  • Formerly EC 3.4.3.7.
 10 A0A140VJR2 A0A140VJR2 A2RS23 A2RS23 P12955 P12955 Q11136 Q11136 Q5I0D7 Q5RFB3