The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Protein tyrosine phosphatase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 40: mRNA-capping enzyme

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 O55236 (/IPI) O55236 (/IPI) O60942 (/IPI) O60942 (/IPI) O60942 (/IPI) O60942 (/IPI) O60942 (/IPI) O60942 (/IPI)
MRNA guanylyltransferase activity GO:0004484
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
6 O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA)
Polynucleotide 5'-phosphatase activity GO:0004651
Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate.
6 O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS)
RNA guanylyltransferase activity GO:0008192
Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule.
6 O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA)
Triphosphatase activity GO:0050355
Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.
6 O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA)
MRNA guanylyltransferase activity GO:0004484
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
4 O55236 (/ISS) O55236 (/ISS) Q6NY98 (/ISS) Q9VY44 (/ISS)
Triphosphatase activity GO:0050355
Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.
3 O55236 (/ISS) O55236 (/ISS) Q6NY98 (/ISS)
MRNA guanylyltransferase activity GO:0004484
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
2 O55236 (/ISO) O55236 (/ISO)
Polynucleotide 5'-phosphatase activity GO:0004651
Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate.
2 Q17607 (/IDA) Q6A3Q2 (/IDA)
RNA guanylyltransferase activity GO:0008192
Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule.
2 O55236 (/ISO) O55236 (/ISO)
Triphosphatase activity GO:0050355
Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.
2 O55236 (/ISO) O55236 (/ISO)
MRNA guanylyltransferase activity GO:0004484
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
1 Q9VY44 (/IGI)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
6 O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
6 O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
6 O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
6 O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
5 O55236 (/ISS) O55236 (/ISS) Q17607 (/ISS) Q6A3Q2 (/ISS) Q6NY98 (/ISS)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
2 O55236 (/ISO) O55236 (/ISO)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
2 O55236 (/ISO) O55236 (/ISO)
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
2 Q17607 (/IDA) Q6A3Q2 (/IDA)
Polynucleotide 5' dephosphorylation GO:0098507
The process of removing one or more phosphate groups from the 5' end of a polynucleotide.
2 Q17607 (/IDA) Q6A3Q2 (/IDA)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
1 Q9VY44 (/IGI)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q17607 (/IGI)
Positive regulation of smoothened signaling pathway GO:0045880
Any process that activates or increases the frequency, rate or extent of smoothened signaling.
1 Q9VY44 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
6 O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
1 Q6A3Q2 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9VY44 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9VY44 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9VY44 (/IDA)