The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Protein tyrosine phosphatase superfamily
".
FunFam 36: Serine/threonine/tyrosine-interacting protein a
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q60969 (/IPI) Q8WUJ0 (/IPI) Q8WUJ0 (/IPI) Q8WUJ0 (/IPI) |
|
Pseudophosphatase activity GO:0001691
Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.
|
3 | Q8WUJ0 (/IMP) Q8WUJ0 (/IMP) Q8WUJ0 (/IMP) |
|
F-box domain binding GO:1990444
Interacting selectively and non-covalently with an F-box domain of a protein.
|
3 | Q8WUJ0 (/IMP) Q8WUJ0 (/IMP) Q8WUJ0 (/IMP) |
|
Pseudophosphatase activity GO:0001691
Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.
|
1 | Q60969 (/ISO) |
|
F-box domain binding GO:1990444
Interacting selectively and non-covalently with an F-box domain of a protein.
|
1 | Q60969 (/ISO) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MAPK export from nucleus GO:0045204
The directed movement of a MAP kinase from the nucleus to the cytoplasm.
|
4 | Q5RDP3 (/ISS) Q5RDP3 (/ISS) Q5RDP3 (/ISS) Q60969 (/ISS) |
|
Regulation of ERK1 and ERK2 cascade GO:0070372
Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
4 | Q5RDP3 (/ISS) Q5RDP3 (/ISS) Q5RDP3 (/ISS) Q60969 (/ISS) |
|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
3 | Q586S8 (/ISM) Q586S8 (/ISM) Q586S8 (/ISM) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
3 | Q8WUJ0 (/IDA) Q8WUJ0 (/IDA) Q8WUJ0 (/IDA) |
|
MAPK export from nucleus GO:0045204
The directed movement of a MAP kinase from the nucleus to the cytoplasm.
|
3 | Q8WUJ0 (/IMP) Q8WUJ0 (/IMP) Q8WUJ0 (/IMP) |
|
Negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process GO:0062026
Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
|
3 | Q8WUJ0 (/IMP) Q8WUJ0 (/IMP) Q8WUJ0 (/IMP) |
|
Regulation of ERK1 and ERK2 cascade GO:0070372
Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
3 | Q8WUJ0 (/IMP) Q8WUJ0 (/IMP) Q8WUJ0 (/IMP) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | Q60969 (/IMP) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
1 | Q60969 (/ISO) |
|
MAPK export from nucleus GO:0045204
The directed movement of a MAP kinase from the nucleus to the cytoplasm.
|
1 | Q60969 (/ISO) |
|
Negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process GO:0062026
Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
|
1 | Q60969 (/ISO) |
|
Regulation of ERK1 and ERK2 cascade GO:0070372
Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | Q60969 (/ISO) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
7 | Q586S8 (/IDA) Q586S8 (/IDA) Q586S8 (/IDA) Q60969 (/IDA) Q8WUJ0 (/IDA) Q8WUJ0 (/IDA) Q8WUJ0 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | A0A024R641 (/IDA) A0A024R641 (/IDA) A0A024R641 (/IDA) Q8WUJ0 (/IDA) Q8WUJ0 (/IDA) Q8WUJ0 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | Q5RDP3 (/ISS) Q5RDP3 (/ISS) Q5RDP3 (/ISS) Q60969 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q8WUJ0 (/IDA) Q8WUJ0 (/IDA) Q8WUJ0 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q5RDP3 (/ISS) Q5RDP3 (/ISS) Q5RDP3 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | E9ACT8 (/ISO) Q60969 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q60969 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q60969 (/ISO) |