The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Diphtheria Toxin, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Diphtheria toxin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
6 P00588 (/IPI) Q6NK15 (/IPI) Q6NK15 (/IPI) Q6NK15 (/IPI) Q6NK15 (/IPI) Q6NK15 (/IPI)
Protein transmembrane transporter activity GO:0008320
Enables the transfer of a protein from one side of a membrane to the other.
1 P00588 (/TAS)
NAD+-diphthamide ADP-ribosyltransferase activity GO:0047286
Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide.
1 P00588 (/EXP)

There are 0 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P00588 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P00588 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P00588 (/TAS)
Endocytic vesicle membrane GO:0030666
The lipid bilayer surrounding an endocytic vesicle.
1 P00588 (/TAS)
Clathrin-coated endocytic vesicle membrane GO:0030669
The lipid bilayer surrounding a clathrin-coated endocytic vesicle.
1 P00588 (/TAS)