The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
glutathione-dependent formaldehyde- activating enzyme (gfa)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
S-(hydroxymethyl)glutathione synthase. [EC: 4.4.1.22]
S-(hydroxymethyl)glutathione = glutathione + formaldehyde.
  • The enzyme from Paracoccus denitrificans accelerates the spontaneous reaction in which the adduct of formaldehyde and glutathione is formed, i.e. the substrate for EC 1.1.1.284, in the formaldehyde- detoxification pathway.
  • Formerly EC 1.2.1.1.
54 A0A093V6R6 A0A0E0UQL8 A0A0E4BL48 A0A0U5FAA2 A0A146F7E0 A0A167RPJ9 A0A1A5J478 A0A1M3TXG6 A0A1S9DAU3 A0A1T1S792
(44 more...)