The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Yeast translation eEF2 (G' domain)
".
FunFam 2: Elongation factor like GTPase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
4 | Q38BE4 (/IDA) Q38BE4 (/IDA) Q38BE4 (/IDA) Q38BE4 (/IDA) |
|
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
4 | Q38BE4 (/ISM) Q38BE4 (/ISM) Q38BE4 (/ISM) Q38BE4 (/ISM) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q7Z2Z2 (/IDA) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q8C0D5 (/ISO) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q8C0D5 (/ISS) |
|
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
|
1 | Q7Z2Z2 (/IMP) |
|
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
|
1 | Q8C0D5 (/ISO) |
|
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
|
1 | Q8C0D5 (/ISS) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
|
4 | Q38BE4 (/ISM) Q38BE4 (/ISM) Q38BE4 (/ISM) Q38BE4 (/ISM) |
|
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
|
1 | Q54JV1 (/IMP) |
|
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P29691 (/IMP) |
|
Mature ribosome assembly GO:0042256
The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.
|
1 | Q7Z2Z2 (/IMP) |
|
Mature ribosome assembly GO:0042256
The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.
|
1 | Q8C0D5 (/ISO) |
|
Mature ribosome assembly GO:0042256
The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.
|
1 | Q8C0D5 (/ISS) |
|
GTP metabolic process GO:0046039
The chemical reactions and pathways involving GTP, guanosine triphosphate.
|
1 | Q7Z2Z2 (/IDA) |
|
GTP metabolic process GO:0046039
The chemical reactions and pathways involving GTP, guanosine triphosphate.
|
1 | Q8C0D5 (/ISO) |
|
GTP metabolic process GO:0046039
The chemical reactions and pathways involving GTP, guanosine triphosphate.
|
1 | Q8C0D5 (/ISS) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
1 | P29691 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q38BE4 (/IDA) Q38BE4 (/IDA) Q38BE4 (/IDA) Q38BE4 (/IDA) |
|
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
4 | Q38BE4 (/IDA) Q38BE4 (/IDA) Q38BE4 (/IDA) Q38BE4 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q95TH3 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | F4J2T9 (/IDA) |