The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Amidase signature (AS) domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17: General amidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amidase activity GO:0004040
Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
3 G5EAW7 (/ISO) G5EAW7 (/ISO) G5EAW7 (/ISO)
Amidase activity GO:0004040
Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
3 G5EAW7 (/RCA) G5EAW7 (/RCA) G5EAW7 (/RCA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Arginine metabolic process GO:0006525
The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
3 G5EAW7 (/RCA) G5EAW7 (/RCA) G5EAW7 (/RCA)
Aromatic amino acid family biosynthetic process GO:0009073
The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
3 G5EAW7 (/RCA) G5EAW7 (/RCA) G5EAW7 (/RCA)
Cellular amide catabolic process GO:0043605
The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
3 G5EAW7 (/IMP) G5EAW7 (/IMP) G5EAW7 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.