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CATH Superfamily 3.90.1200.10

Aminoglycoside phosphotransferase (APH), C-terminal lobe

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36: N-acetylhexosamine 1-kinase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
N-acetylhexosamine 1-kinase. [EC: 2.7.1.162]
ATP + N-acetyl-D-hexosamine = ADP + N-acetyl-alpha-D-hexosamine 1-phosphate.
  • Involved in the lacto-N-biose I/galacto-N-biose degradation pathway in the probiotic bacterium Bifidobacterium longum.
  • Differs from EC 2.7.1.157 as it can phosphorylate both N-acetylgalactosamine and N-acetylglucosamine at similar rates.
  • Also has some activity with N-acetyl-D-mannosamine, D-talose and D-mannose as substrate.
  • ATP can be replaced by GTP or ITP but with decreased enzyme activity.
 4 A0A413AI77 A0A413AI77 E8MF12 E8MF12