View in Gene3D

CATH Superfamily 3.90.1170.50

Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 7: Aldehyde oxidase1

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Indole-3-acetaldehyde oxidase. [EC: 1.2.3.7]
(Indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2).
  • Isoform of EC 1.2.3.1.
  • Has a preference for aldehydes having an indole-ring structure as substrate.
  • May play a role in plant hormone biosynthesis as its activity is higher in the auxin-overproducing mutant, super-root1, than in wild- type Arabidopsis thaliana.
  • While (indol-3-yl)acetaldehyde is the preferred substrate, it also oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly.
 2 O23887 O23888