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CATH Superfamily 3.90.1170.20

Quinolinate phosphoribosyl transferase, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Quinolinate phosphoribosyl transferase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Nicotinate-nucleotide pyrophosphorylase [carboxyla...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nicotinate-nucleotide diphosphorylase (carboxylating) activity GO:0004514
Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate.
 46 P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA)
(36 more)
Nicotinate-nucleotide diphosphorylase (carboxylating) activity GO:0004514
Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate.
 7 Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NAD biosynthetic process GO:0009435
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
 46 P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA)
(36 more)
'de novo' NAD biosynthetic process from aspartate GO:0034628
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
 46 P30011 (/IMP) P30011 (/IMP) P30011 (/IMP) P30011 (/IMP) P30011 (/IMP) P30011 (/IMP) P30011 (/IMP) P30011 (/IMP) P30011 (/IMP) P30011 (/IMP)
(36 more)
NADH metabolic process GO:0006734
The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
 7 Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS)
NADP metabolic process GO:0006739
The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
 7 Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS) Q9KPE6 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 46 P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA)
(36 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 46 P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA) P30011 (/IDA)
(36 more)