The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ribonuclease Inhibitor
".
FunFam 82: Leucine-rich repeat-containing 24
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Epidermal growth factor receptor binding GO:0005154
Interacting selectively and non-covalently with the epidermal growth factor receptor.
|
4 | P91643 (/IPI) Q2XY32 (/IPI) Q8T3J2 (/IPI) Q9VK54 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | A0A0R4IC56 (/IPI) A8BB30 (/IPI) P91643 (/IPI) |
|
Receptor antagonist activity GO:0048019
The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
|
3 | P91643 (/IDA) Q2XY32 (/IDA) Q8T3J2 (/IDA) |
|
Neurotrophin receptor activity GO:0005030
Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity.
|
1 | A0A0B4KHL5 (/IDA) |
|
Receptor inhibitor activity GO:0030547
The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is decreased.
|
1 | Q9VK54 (/IDA) |
|
Neurotrophin binding GO:0043121
Interacting selectively and non-covalently with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.
|
1 | A0A0B4KHL5 (/IPI) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of epidermal growth factor-activated receptor activity GO:0007175
Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity.
|
1 | Q9VK54 (/IDA) |
|
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
|
1 | Q9VK54 (/IDA) |
|
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
|
1 | Q9VK54 (/IGI) |
|
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
|
1 | Q9VK54 (/IMP) |
|
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
1 | A0A0B4KHL5 (/IMP) |
|
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
|
1 | Q9VK54 (/IMP) |
|
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
1 | Q8BHA1 (/IDA) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
11 |
A0A0B4KHL5 (/ISM)
P91643 (/ISM)
P91644 (/ISM)
Q2XY26 (/ISM)
Q2XY32 (/ISM)
Q8T3J2 (/ISM)
Q9V430 (/ISM)
Q9V9V6 (/ISM)
Q9VK22 (/ISM)
Q9VK54 (/ISM)
(1 more) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9VK54 (/IDA) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q9VK54 (/IDA) |
|
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
1 | A0A0B4KHL5 (/IDA) |
|
Type I terminal bouton GO:0061174
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
|
1 | A0A0B4KHL5 (/IDA) |