The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Inhibitor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 572: Ran GTPase-activating protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
8 P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P41391 (/IDA)
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
7 P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP)
Ran GTPase binding GO:0008536
Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.
7 P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosomal subunit export from nucleus GO:0000054
The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.
7 P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP)
Chromatin silencing at telomere GO:0006348
Repression of transcription of telomeric DNA by altering the structure of chromatin.
7 P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP)
RNA import into nucleus GO:0006404
The import of RNA from the cytoplasm to the nucleus.
7 P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP)
RRNA export from nucleus GO:0006407
The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins.
7 P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP)
TRNA export from nucleus GO:0006409
The directed movement of tRNA from the nucleus to the cytoplasm.
7 P11745 (/IGI) P11745 (/IGI) P11745 (/IGI) P11745 (/IGI) P11745 (/IGI) P11745 (/IGI) P11745 (/IGI)
TRNA export from nucleus GO:0006409
The directed movement of tRNA from the nucleus to the cytoplasm.
7 P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
7 P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA)
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
7 P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA)
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
7 P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP) P11745 (/IMP)
Positive regulation of protein export from nucleus GO:0046827
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.
1 P41391 (/IDA)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P41391 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA) P11745 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P41391 (/IDA) Q5B3L8 (/IDA) Q5B3L8 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P41391 (/HDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 P41391 (/IDA)