The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ribonuclease Inhibitor
".
FunFam 397: Transforming growth factor beta activator LRRC32
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transforming growth factor beta binding GO:0050431
Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
|
3 | G3XA59 (/IPI) Q14392 (/IPI) Q14392 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q14392 (/IPI) Q14392 (/IPI) |
|
Transforming growth factor beta binding GO:0050431
Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
|
2 | Q14392 (/IDA) Q14392 (/IDA) |
|
Transforming growth factor beta binding GO:0050431
Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
|
2 | Q5RF01 (/ISS) Q5RF01 (/ISS) |
|
Transforming growth factor beta binding GO:0050431
Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
|
1 | G3XA59 (/ISO) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Secondary palate development GO:0062009
The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.
|
4 | Q14392 (/ISS) Q14392 (/ISS) Q5RF01 (/ISS) Q5RF01 (/ISS) |
|
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
3 | G3XA59 (/ISS) Q5RF01 (/ISS) Q5RF01 (/ISS) |
|
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q14392 (/IDA) Q14392 (/IDA) |
|
Regulation of transforming growth factor beta activation GO:1901388
Any process that modulates the frequency, rate or extent of transforming growth factor beta activation.
|
2 | Q14392 (/IDA) Q14392 (/IDA) |
|
Regulation of transforming growth factor beta activation GO:1901388
Any process that modulates the frequency, rate or extent of transforming growth factor beta activation.
|
2 | Q5RF01 (/ISS) Q5RF01 (/ISS) |
|
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | G3XA59 (/ISO) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | G3XA59 (/IDA) |
|
Platelet activation GO:0030168
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
|
1 | E7FFN8 (/IMP) |
|
Negative regulation of activated T cell proliferation GO:0046007
Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation.
|
1 | G3XA59 (/IDA) |
|
Negative regulation of cytokine secretion GO:0050710
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cytokines from a cell.
|
1 | G3XA59 (/IDA) |
|
Secondary palate development GO:0062009
The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.
|
1 | G3XA59 (/IMP) |
|
Regulation of transforming growth factor beta activation GO:1901388
Any process that modulates the frequency, rate or extent of transforming growth factor beta activation.
|
1 | G3XA59 (/ISO) |
|
Regulation of transforming growth factor beta3 activation GO:1901398
Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation.
|
1 | G3XA59 (/IDA) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | A0A024R5J7 (/IDA) A0A024R5J7 (/IDA) Q14392 (/IDA) Q14392 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
3 | G3XA59 (/ISS) Q5RF01 (/ISS) Q5RF01 (/ISS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q14392 (/TAS) Q14392 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | Q14392 (/IDA) Q14392 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | G3XA59 (/ISO) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | G3XA59 (/ISO) |