The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Inhibitor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 331: Dynein assembly factor 1, axonemal homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Dynein complex binding GO:0070840
Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.
8 B3NLX1 (/ISS) B4GT53 (/ISS) B4P6W7 (/ISS) B6D5P6 (/ISS) Q16RY9 (/ISS) Q29KL8 (/ISS) Q7PK92 (/ISS) Q8INT5 (/ISS)
Dynein complex binding GO:0070840
Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.
1 Q7ZV84 (/IMP)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
8 B3NLX1 (/ISS) B4GT53 (/ISS) B4P6W7 (/ISS) B6D5P6 (/ISS) Q16RY9 (/ISS) Q29KL8 (/ISS) Q7PK92 (/ISS) Q8INT5 (/ISS)
Cilium movement GO:0003341
The directed, self-propelled movement of a cilium.
2 Q09JZ4 (/IMP) Q09JZ4 (/IMP)
Regulation of cilium beat frequency GO:0003356
Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium.
2 Q09JZ4 (/IMP) Q09JZ4 (/IMP)
Protein localization to organelle GO:0033365
A process in which a protein is transported to, or maintained in, a location within an organelle.
2 Q09JZ4 (/IMP) Q09JZ4 (/IMP)
Axonemal dynein complex assembly GO:0070286
The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
2 Q09JZ4 (/IMP) Q09JZ4 (/IMP)
Positive regulation of cilium-dependent cell motility GO:2000155
Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility.
2 Q09JZ4 (/IMP) Q09JZ4 (/IMP)
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
1 Q7ZV84 (/IMP)
Embryonic heart tube morphogenesis GO:0003143
The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
1 Q7ZV84 (/IMP)
Heart jogging GO:0003146
The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.
1 Q7ZV84 (/IMP)
Cell migration involved in heart jogging GO:0003305
The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging.
1 Q7ZV84 (/IMP)
Heart rudiment morphogenesis GO:0003314
The process in which the anatomical structures of the heart rudiment are generated and organized.
1 Q7ZV84 (/IMP)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 Q8INT5 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q7ZV84 (/IMP)
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
1 Q7ZV84 (/IMP)
Gastrulation GO:0007369
A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
1 Q7ZV84 (/IMP)
Axoneme assembly GO:0035082
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
1 Q7ZV84 (/IMP)
Pronephros development GO:0048793
The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
1 Q7ZV84 (/IMP)
Convergent extension involved in gastrulation GO:0060027
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
1 Q7ZV84 (/IMP)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
1 Q7ZV84 (/IMP)
Determination of heart left/right asymmetry GO:0061371
Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.
1 Q7ZV84 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
9 B3NLX1 (/ISS) B4GT53 (/ISS) B4P6W7 (/ISS) B6D5P6 (/ISS) Q16RY9 (/ISS) Q29KL8 (/ISS) Q7PK92 (/ISS) Q7ZV84 (/ISS) Q8INT5 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q09JZ4 (/IDA) Q09JZ4 (/IDA)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
2 Q09JZ4 (/IDA) Q09JZ4 (/IDA)