Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.

Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.

The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.

The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.

Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.

Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.

The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.

Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.

Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.

Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.

Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.

Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.

Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.

The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.

Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.

Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.

Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.

Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.

The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.

Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.

Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.

Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.

Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.

Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.

Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.

Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.

Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.

Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.

Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.

Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.

Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.

An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Cytoplasm situated near, or occurring around, the nucleus.

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

Cytoplasm situated near, or occurring around, the nucleus.

Cytoplasm situated near, or occurring around, the nucleus.