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CATH Superfamily 3.80.10.10

Ribonuclease Inhibitor

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Inhibitor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 223: Leucine-rich repeat-containing 8 VRAC subunit A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Volume-sensitive anion channel activity GO:0005225
Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
 14 Q4V8W3 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP)
(4 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 14 Q80WG5 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI)
(4 more)
Volume-sensitive anion channel activity GO:0005225
Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
 13 Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS)
(3 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 13 Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI) Q8IWT6 (/IPI)
(3 more)
Volume-sensitive anion channel activity GO:0005225
Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
 1 Q80WG5 (/IDA)
Volume-sensitive anion channel activity GO:0005225
Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
 1 Q80WG5 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 1 Q80WG5 (/ISO)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pre-B cell differentiation GO:0002329
The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
 13 Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS)
(3 more)
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 13 Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP)
(3 more)
Cell volume homeostasis GO:0006884
Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.
 13 Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP)
(3 more)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
 13 Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP)
(3 more)
Protein hexamerization GO:0034214
The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
 13 Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS)
(3 more)
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
 13 Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS)
(3 more)
Anion transmembrane transport GO:0098656
The process in which an anion is transported across a membrane.
 13 Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP) Q8IWT6 (/IMP)
(3 more)
Anion transmembrane transport GO:0098656
The process in which an anion is transported across a membrane.
 13 Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS)
(3 more)
Pre-B cell differentiation GO:0002329
The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
 1 Q80WG5 (/IMP)
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 1 Q80WG5 (/ISO)
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 1 Q80WG5 (/ISS)
Cell volume homeostasis GO:0006884
Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.
 1 Q80WG5 (/ISO)
Cell volume homeostasis GO:0006884
Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.
 1 Q80WG5 (/ISS)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
 1 Q80WG5 (/ISO)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
 1 Q80WG5 (/ISS)
Taurine transport GO:0015734
The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 1 Q80WG5 (/ISO)
Aspartate transmembrane transport GO:0015810
The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other.
 1 Q80WG5 (/ISO)
Protein hexamerization GO:0034214
The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
 1 Q80WG5 (/IDA)
Anion transmembrane transport GO:0098656
The process in which an anion is transported across a membrane.
 1 Q80WG5 (/IDA)
Anion transmembrane transport GO:0098656
The process in which an anion is transported across a membrane.
 1 Q80WG5 (/ISO)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ion channel complex GO:0034702
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
 14 Q80WG5 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA)
(4 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 13 Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA)
(3 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 13 Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS) Q8IWT6 (/TAS)
(3 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 13 Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS) Q8IWT6 (/ISS)
(3 more)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
 13 Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA) Q8IWT6 (/IDA)
(3 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 13 Q8IWT6 (/HDA) Q8IWT6 (/HDA) Q8IWT6 (/HDA) Q8IWT6 (/HDA) Q8IWT6 (/HDA) Q8IWT6 (/HDA) Q8IWT6 (/HDA) Q8IWT6 (/HDA) Q8IWT6 (/HDA) Q8IWT6 (/HDA)
(3 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 1 Q80WG5 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 1 Q80WG5 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 1 Q80WG5 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 1 Q80WG5 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
 1 Q80WG5 (/ISO)
Ion channel complex GO:0034702
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
 1 Q80WG5 (/ISO)
Ion channel complex GO:0034702
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
 1 Q80WG5 (/ISS)