The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Inhibitor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 204: Scribbled, isoform O

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q7KRY7 (/IPI)

There are 43 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q7KRY7 (/IMP)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
1 Q7KRY7 (/IMP)
Cell fate specification GO:0001708
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
1 Q7KRY7 (/IMP)
Establishment of imaginal disc-derived wing hair orientation GO:0001737
Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.
1 Q7KRY7 (/IMP)
Morphogenesis of a polarized epithelium GO:0001738
The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.
1 Q7KRY7 (/TAS)
Pole plasm protein localization GO:0007318
Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
1 Q7KRY7 (/IMP)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
1 Q7KRY7 (/IMP)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
1 Q7KRY7 (/TAS)
R3/R4 cell fate commitment GO:0007464
The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres.
1 Q7KRY7 (/IMP)
Wing disc morphogenesis GO:0007472
The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura.
1 Q7KRY7 (/IMP)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
1 Q7KRY7 (/IMP)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q7KRY7 (/IMP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q7KRY7 (/IMP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q7KRY7 (/TAS)
Regulation of Notch signaling pathway GO:0008593
Any process that modulates the frequency, rate or extent of the Notch signaling pathway.
1 Q7KRY7 (/IMP)
Morphogenesis of embryonic epithelium GO:0016331
The process in which the anatomical structures of embryonic epithelia are generated and organized.
1 Q7KRY7 (/TAS)
Establishment or maintenance of polarity of embryonic epithelium GO:0016332
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo.
1 Q7KRY7 (/TAS)
Morphogenesis of follicular epithelium GO:0016333
The process in which the anatomical structures of a follicular epithelium are generated and organized.
1 Q7KRY7 (/IMP)
Establishment or maintenance of polarity of follicular epithelium GO:0016334
Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet.
1 Q7KRY7 (/IMP)
Morphogenesis of larval imaginal disc epithelium GO:0016335
The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.
1 Q7KRY7 (/IMP)
Establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016336
Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium.
1 Q7KRY7 (/IMP)
Septate junction assembly GO:0019991
The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.
1 Q7KRY7 (/IMP)
Regulation of endocytosis GO:0030100
Any process that modulates the frequency, rate or extent of endocytosis.
1 Q7KRY7 (/IMP)
Ovarian follicle cell development GO:0030707
The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.
1 Q7KRY7 (/IMP)
Anterior/posterior axis specification, follicular epithelium GO:0030714
Polarization of the follicle cells of an insect ovary along the anterior/posterior axis.
1 Q7KRY7 (/IMP)
Establishment or maintenance of apical/basal cell polarity GO:0035088
Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.
1 Q7KRY7 (/IMP)
Olfactory behavior GO:0042048
The behavior of an organism in response to an odor.
1 Q7KRY7 (/IMP)
Regulation of epidermal growth factor receptor signaling pathway GO:0042058
Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
1 Q7KRY7 (/IMP)
Establishment of ommatidial planar polarity GO:0042067
The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.
1 Q7KRY7 (/IMP)
Basal protein localization GO:0045175
Any process in which a protein is transported to, or maintained in, basal regions of the cell.
1 Q7KRY7 (/IMP)
Zonula adherens assembly GO:0045186
Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
1 Q7KRY7 (/IMP)
Establishment or maintenance of epithelial cell apical/basal polarity GO:0045197
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
1 Q7KRY7 (/TAS)
Establishment of epithelial cell apical/basal polarity GO:0045198
The specification and formation of the apicobasal polarity of an epithelial cell.
1 Q7KRY7 (/IMP)
Negative regulation of imaginal disc growth GO:0045571
Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.
1 Q7KRY7 (/IMP)
Regulation of receptor signaling pathway via JAK-STAT GO:0046425
Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT.
1 Q7KRY7 (/IMP)
Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
1 Q7KRY7 (/IMP)
Stem cell differentiation GO:0048863
The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
1 Q7KRY7 (/IMP)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
1 Q7KRY7 (/IMP)
Regulation of synapse structure or activity GO:0050803
Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
1 Q7KRY7 (/IMP)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
1 Q7KRY7 (/NAS)
Cell fate commitment involved in pattern specification GO:0060581
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.
1 Q7KRY7 (/IMP)
Malpighian tubule development GO:0072002
The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
1 Q7KRY7 (/IMP)
Stem cell proliferation GO:0072089
The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
1 Q7KRY7 (/IMP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Septate junction GO:0005918
A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods.
1 Q7KRY7 (/IDA)
Septate junction GO:0005918
A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods.
1 Q7KRY7 (/NAS)
Septate junction GO:0005918
A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods.
1 Q7KRY7 (/TAS)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 Q7KRY7 (/IDA)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 Q7KRY7 (/IDA)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 Q7KRY7 (/TAS)
Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
1 Q7KRY7 (/IDA)
Lateral plasma membrane GO:0016328
The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.
1 Q7KRY7 (/IDA)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
1 Q7KRY7 (/IDA)
Fusome GO:0045169
A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle.
1 Q7KRY7 (/IDA)
Basolateral part of cell GO:1990794
The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells.
1 Q7KRY7 (/IDA)