The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ribonuclease Inhibitor
".
FunFam 166: Dynein assembly factor 1, axonemal
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Dynein complex binding GO:0070840
Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.
|
10 | B3NLX1 (/ISS) B4GT53 (/ISS) B4P6W7 (/ISS) B6D5P1 (/ISS) B6D5P3 (/ISS) B6D5P6 (/ISS) Q16RY9 (/ISS) Q29KL8 (/ISS) Q7PK92 (/ISS) Q8INT5 (/ISS) |
Dynein complex binding GO:0070840
Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.
|
3 | Q7ZV84 (/IMP) Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
There are 27 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
10 | B3NLX1 (/ISS) B4GT53 (/ISS) B4P6W7 (/ISS) B6D5P1 (/ISS) B6D5P3 (/ISS) B6D5P6 (/ISS) Q16RY9 (/ISS) Q29KL8 (/ISS) Q7PK92 (/ISS) Q8INT5 (/ISS) |
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
|
3 | Q7ZV84 (/IMP) Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
3 | Q7ZV84 (/IMP) Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Cilium movement GO:0003341
The directed, self-propelled movement of a cilium.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Regulation of cilium beat frequency GO:0003356
Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Determination of pancreatic left/right asymmetry GO:0035469
Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Outer dynein arm assembly GO:0036158
The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Inner dynein arm assembly GO:0036159
The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Motile cilium assembly GO:0044458
The aggregation, arrangement and bonding together of a set of components to form a motile cilium.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Epithelial cilium movement involved in determination of left/right asymmetry GO:0060287
The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves.
|
2 | Q8NEP3 (/IC) Q8NEP3 (/IC) |
Left/right pattern formation GO:0060972
The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Axonemal dynein complex assembly GO:0070286
The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Determination of digestive tract left/right asymmetry GO:0071907
Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Determination of liver left/right asymmetry GO:0071910
Determination of the asymmetric location of the liver with respect to the left and right halves of the organism.
|
2 | Q8NEP3 (/IMP) Q8NEP3 (/IMP) |
Embryonic heart tube morphogenesis GO:0003143
The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
|
1 | Q7ZV84 (/IMP) |
Heart jogging GO:0003146
The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.
|
1 | Q7ZV84 (/IMP) |
Cell migration involved in heart jogging GO:0003305
The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging.
|
1 | Q7ZV84 (/IMP) |
Heart rudiment morphogenesis GO:0003314
The process in which the anatomical structures of the heart rudiment are generated and organized.
|
1 | Q7ZV84 (/IMP) |
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
1 | Q8INT5 (/IMP) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | Q7ZV84 (/IMP) |
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
|
1 | Q7ZV84 (/IMP) |
Gastrulation GO:0007369
A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
|
1 | Q7ZV84 (/IMP) |
Axoneme assembly GO:0035082
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
|
1 | Q7ZV84 (/IMP) |
Pronephros development GO:0048793
The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
|
1 | Q7ZV84 (/IMP) |
Convergent extension involved in gastrulation GO:0060027
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
|
1 | Q7ZV84 (/IMP) |
Determination of heart left/right asymmetry GO:0061371
Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.
|
1 | Q7ZV84 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
|
11 |
B3NLX1 (/ISS)
B4GT53 (/ISS)
B4P6W7 (/ISS)
B6D5P1 (/ISS)
B6D5P3 (/ISS)
B6D5P6 (/ISS)
Q16RY9 (/ISS)
Q29KL8 (/ISS)
Q7PK92 (/ISS)
Q7ZV84 (/ISS)
(1 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | A0A140VJN4 (/IDA) A0A140VJN4 (/IDA) Q8NEP3 (/IDA) Q8NEP3 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | A0A140VJN4 (/IDA) A0A140VJN4 (/IDA) Q8NEP3 (/IDA) Q8NEP3 (/IDA) |
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
4 | A0A140VJN4 (/IDA) A0A140VJN4 (/IDA) Q8NEP3 (/IDA) Q8NEP3 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q8NEP3 (/NAS) Q8NEP3 (/NAS) |
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
|
2 | Q8NEP3 (/IDA) Q8NEP3 (/IDA) |