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CATH Superfamily 3.60.9.10

Aldehyde ferredoxin oxidoreductase, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldehyde ferredoxin oxidoreductase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aldehyde ferredoxin oxidoreductase. [EC: 1.2.7.5]
An aldehyde + H(2)O + 2 oxidized ferredoxin = a carboxylate + 2 H(+) + 2 reduced ferredoxin.
  • This is an oxygen-sensitive enzyme.
  • Catalyzes the oxidation of aldehydes (including crotonaldehyde, acetaldehyde, formaldehyde and glyceraldehyde) to their corresponding acids.
  • However, it does not oxidize glyceraldehyde 3-phosphate (see EC 1.2.7.6).
  • Can use ferredoxin or methylviologen but not NAD(P)(+) as electron acceptor.
 6 I6UX53 O58778 Q51739 Q56303 Q5JE15 Q9V035
Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin). [EC: 1.2.7.6]
D-glyceraldehyde-3-phosphate + H(2)O + 2 oxidized ferredoxin = 3-phospho- D-glycerate + 2 H(+) + 2 reduced ferredoxin.
  • Thought to function in place of glyceraldehyde-3-phosphate dehydrogenase and possibly phosphoglycerate kinase in the novel Embden-Meyerhof-type glycolytic pathway found in Pyrococcus furiosus.
  • Specific for glyceraldehyde-3-phosphate.
 2 I6UZU7 Q8U3K2