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CATH Superfamily 3.60.60.10

Penicillin V Acylase; Chain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Penicillin V Acylase; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ceramidase. [EC: 3.5.1.23]
N-acylsphingosine + H(2)O = a carboxylate + sphingosine.
    		 7 A0A383ZFX3 A5A6P2 H9FUK7 K7C301 Q13510 Q17QB3 Q60HH4
    Choloylglycine hydrolase. [EC: 3.5.1.24]
    3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H(2)O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine.
    • Also acts on the 3-alpha,12-alpha-dihydroxy-derivative, and on choloyl-taurine.
    		 7 A0A0H2YTH6 A0A336Q1V0 B1BP69 B1UZB0 B9V401 P54965 Q06115
    Isopenicillin-N N-acyltransferase. [EC: 2.3.1.164]
    Phenylacetyl-CoA + isopenicillin N + H(2)O = CoA + penicillin G + L-2- aminohexanedioate.
    • Proceeds by a two stage mechanism via 6-aminopenicillanic acid.
    • Different from EC 3.5.1.11.
    		 4 B6HLT9 P15802 P21133 Q3HUS0
    Penicillin amidase. [EC: 3.5.1.11]
    Penicillin + H(2)O = a carboxylate + 6-aminopenicillanate.
      		 1 P12256