The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
PPM-type phosphatase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 40: Protein serine/threonine phosphatase 2C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
1 Q12511 (/IDA)
[pyruvate dehydrogenase (lipoamide)] phosphatase activity GO:0004741
Catalysis of the reaction:
1 Q12511 (/IMP)
[pyruvate dehydrogenase (lipoamide)] phosphatase activity GO:0004741
Catalysis of the reaction:
1 O14189 (/ISO)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of spore germination GO:1904359
Any process that modulates the frequency, rate or extent of spore germination.
2 Q5B158 (/IMP) Q5B158 (/IMP)
Generation of precursor metabolites and energy GO:0006091
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
1 O14189 (/NAS)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
1 Q12511 (/IDA)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q5A388 (/IMP)
Peptidyl-serine dephosphorylation GO:0070262
The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.
1 Q12511 (/IMP)
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 Q5A388 (/IMP)
Positive regulation of pyruvate dehydrogenase activity GO:1904184
Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity.
1 Q12511 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 O14189 (/HDA) Q12511 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q12511 (/IDA) Q5A388 (/IDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
1 Q12511 (/IDA)