The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Integrator complex subunit 11

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q5TA45 (/IPI) Q5TA45 (/IPI)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
SnRNA processing GO:0016180
Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule.
3 Q5ZIH0 (/ISS) Q9CWS4 (/ISS) Q9VAH9 (/ISS)
SnRNA processing GO:0016180
Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule.
2 Q5TA45 (/IDA) Q5TA45 (/IDA)
SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
2 Q5TA45 (/TAS) Q5TA45 (/TAS)
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
1 Q9VAH9 (/ISS)
SnRNA processing GO:0016180
Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule.
1 Q9CWS4 (/ISO)
SnRNA 3'-end processing GO:0034472
Any process involved in forming the mature 3' end of an snRNA molecule.
1 Q9VAH9 (/IDA)
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
1 Q503E1 (/IMP)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 Q2YDM2 (/ISS) Q3MHC2 (/ISS) Q5NVE6 (/ISS) Q5NVE6 (/ISS) Q9CWS4 (/ISS) Q9VAH9 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 Q2YDM2 (/ISS) Q3MHC2 (/ISS) Q5NVE6 (/ISS) Q5NVE6 (/ISS) Q9CWS4 (/ISS) Q9VAH9 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 A0A024R0F2 (/IDA) A0A024R0F2 (/IDA) Q5TA45 (/IDA) Q5TA45 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 A0A024R0F2 (/IDA) A0A024R0F2 (/IDA) Q5TA45 (/IDA) Q5TA45 (/IDA)
Integrator complex GO:0032039
A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.
3 Q5ZIH0 (/ISS) Q9CWS4 (/ISS) Q9VAH9 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q5TA45 (/IDA) Q5TA45 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q5TA45 (/TAS) Q5TA45 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q5TA45 (/IDA) Q5TA45 (/IDA)
Integrator complex GO:0032039
A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.
2 Q5TA45 (/IDA) Q5TA45 (/IDA)
Blood microparticle GO:0072562
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
2 Q5TA45 (/HDA) Q5TA45 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9CWS4 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9CWS4 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9CWS4 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9CWS4 (/ISO)
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
1 Q9VAH9 (/ISS)
Integrator complex GO:0032039
A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.
1 Q9CWS4 (/ISO)