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CATH Superfamily 3.60.110.10

Carbon-nitrogen hydrolase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Carbon-nitrogen hydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Cyanide hydratase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Cyanide hydratase. [EC: 4.2.1.66]
Formamide = cyanide + H(2)O.
    		 23 A0A0B0DVE4 A0A0B0DVE4 A0A146FAS6 A0A146FAS6 A0A146FAS6 A0A146FAS6 A0A319BA22 A0A319BA22 A0A319BA22 A0A319BA22
    (13 more...)
    Nitrilase. [EC: 3.5.5.1]
    A nitrile + 2 H(2)O = a carboxylate + NH(3).
    • Acts on a wide range of aromatic nitriles including (indol-3- yl)acetonitrile, and also on some aliphatic nitriles, and on the corresponding acid amides (cf. EC 4.2.1.84).
    		 2 Q89GE3 V5IPE4
    Arylacetonitrilase. [EC: 3.5.5.5]
    4-chlorophenylacetonitrile + 2 H(2)O = 4-chlorophenylacetate + NH(3).
    • Requires thiol compounds.
    • Also hydrolyzes other 4-substituted phenylacetonitriles, thien-2- ylacetonitrile, tolylacetonitriles, and, more slowly, benzyl cyanide.
    		 1 V5IPE4