The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Endonuclease/exonuclease/phosphatase
".
FunFam 8: Synaptojanin 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity GO:0004439
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.
|
1 | Q9D2G5 (/IDA) |
|
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity GO:0004439
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.
|
1 | O15056 (/TAS) |
|
Inositol-polyphosphate 5-phosphatase activity GO:0004445
Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
|
1 | O55207 (/IDA) |
|
Inositol-polyphosphate 5-phosphatase activity GO:0004445
Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
|
1 | Q9D2G5 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O15056 (/IPI) |
|
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
|
1 | O55207 (/IPI) |
|
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
|
1 | Q9D2G5 (/ISO) |
|
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
|
1 | O55207 (/IPI) |
|
Phosphatidylinositol monophosphate phosphatase activity GO:0052744
Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate.
|
1 | O55207 (/IDA) |
|
Phosphatidylinositol monophosphate phosphatase activity GO:0052744
Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate.
|
1 | Q9D2G5 (/ISO) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphatidylinositol biosynthetic process GO:0006661
The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
|
1 | O15056 (/TAS) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | O55207 (/IEP) |
|
Inositol phosphate dephosphorylation GO:0046855
The process of removing a phosphate group from any mono- or polyphosphorylated inositol.
|
1 | O55207 (/IDA) |
|
Inositol phosphate dephosphorylation GO:0046855
The process of removing a phosphate group from any mono- or polyphosphorylated inositol.
|
1 | Q9D2G5 (/ISO) |
|
Phosphatidylinositol dephosphorylation GO:0046856
The process of removing one or more phosphate groups from a phosphatidylinositol.
|
1 | O55207 (/IDA) |
|
Phosphatidylinositol dephosphorylation GO:0046856
The process of removing one or more phosphate groups from a phosphatidylinositol.
|
1 | Q9D2G5 (/ISO) |
|
Intracellular distribution of mitochondria GO:0048312
Any process that establishes the spatial arrangement of mitochondria within the cell.
|
1 | O55207 (/IDA) |
|
Intracellular distribution of mitochondria GO:0048312
Any process that establishes the spatial arrangement of mitochondria within the cell.
|
1 | Q9D2G5 (/ISO) |
|
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
|
1 | O15056 (/TAS) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O55207 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9D2G5 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O15056 (/TAS) |
|
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
|
1 | O55207 (/IDA) |
|
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
|
1 | Q9D2G5 (/ISO) |
|
Extrinsic component of mitochondrial outer membrane GO:0031315
The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
1 | O55207 (/IDA) |
|
Extrinsic component of mitochondrial outer membrane GO:0031315
The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
1 | Q9D2G5 (/ISO) |
|
Ruffle membrane GO:0032587
The portion of the plasma membrane surrounding a ruffle.
|
1 | O55207 (/IDA) |
|
Ruffle membrane GO:0032587
The portion of the plasma membrane surrounding a ruffle.
|
1 | Q9D2G5 (/ISO) |
|
Axon terminus GO:0043679
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
|
1 | O55207 (/IDA) |
|
Axon terminus GO:0043679
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
|
1 | Q9D2G5 (/ISO) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | O55207 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q9D2G5 (/ISO) |
|
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
|
1 | O55207 (/IDA) |
|
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
|
1 | Q9D2G5 (/ISO) |