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CATH Superfamily 3.50.50.60

FAD/NAD(P)-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 77: Glutamate synthase small subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutamate synthase (NADPH) activity GO:0004355
Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+.
 46 P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA)
(36 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 46 P09832 (/IPI) P09832 (/IPI) P09832 (/IPI) P09832 (/IPI) P09832 (/IPI) P09832 (/IPI) P09832 (/IPI) P09832 (/IPI) P09832 (/IPI) P09832 (/IPI)
(36 more)
Glutamate synthase (NADPH) activity GO:0004355
Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+.
 3 Q8EHA5 (/ISS) Q9KPJ0 (/ISS) Q9KPJ0 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutamate biosynthetic process GO:0006537
The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.
 46 P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA)
(36 more)
Glutamate biosynthetic process GO:0006537
The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.
 3 Q8EHA5 (/ISS) Q9KPJ0 (/ISS) Q9KPJ0 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 46 P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA) P09832 (/IDA)
(36 more)