The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"FAD/NAD(P)-binding domain
".
FunFam 325: Squalene monooxygenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Squalene monooxygenase activity GO:0004506
Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+).
|
7 | P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) |
|
Squalene monooxygenase activity GO:0004506
Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+).
|
7 | P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) |
|
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
|
7 | P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ergosterol biosynthetic process GO:0006696
The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.
|
7 | P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) P32476 (/IMP) |
|
Ergosterol metabolic process GO:0008204
The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light.
|
2 | O13306 (/IMP) O13306 (/IMP) |
|
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
2 | O13306 (/IMP) O13306 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
7 | P32476 (/HDA) P32476 (/HDA) P32476 (/HDA) P32476 (/HDA) P32476 (/HDA) P32476 (/HDA) P32476 (/HDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
7 | P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) |
|
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
|
7 | P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) P32476 (/IDA) |