The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
IlvD/EDD C-terminal domain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Dihydroxy-acid dehydratase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 16 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphogluconate dehydratase activity GO:0004456
Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O.
106 P0ADF6 (/IDA) P0ADF6 (/IDA) P0ADF6 (/IDA) P0ADF6 (/IDA) P0ADF6 (/IDA) P0ADF6 (/IDA) P0ADF6 (/IDA) P0ADF6 (/IDA) P0ADF6 (/IDA) P0ADF6 (/IDA)
(96 more)
Phosphogluconate dehydratase activity GO:0004456
Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O.
106 P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP)
(96 more)
Dihydroxy-acid dehydratase activity GO:0004160
Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.
26 P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA)
(16 more)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
16 P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA)
(6 more)
Iron-sulfur cluster binding GO:0051536
Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms.
15 P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA)
(5 more)
Dihydroxy-acid dehydratase activity GO:0004160
Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.
8 Q10318 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P9WKJ5 (/IPI) P9WKJ5 (/IPI) P9WKJ5 (/IPI) P9WKJ5 (/IPI) P9WKJ5 (/IPI) P9WKJ5 (/IPI) P9WKJ5 (/IPI) P9WKJ5 (/IPI)
Dihydroxy-acid dehydratase activity GO:0004160
Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.
6 P39522 (/IMP) P39522 (/IMP) P39522 (/IMP) Q4X099 (/IMP) Q4X099 (/IMP) Q4X099 (/IMP)
Dihydroxy-acid dehydratase activity GO:0004160
Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.
4 Q5AZD4 (/ISA) Q5AZD4 (/ISA) Q5B2U2 (/ISA) Q5B2U2 (/ISA)
Phosphogluconate dehydratase activity GO:0004456
Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O.
3 Q9KV69 (/ISS) Q9KV69 (/ISS) Q9KV69 (/ISS)
Dihydroxy-acid dehydratase activity GO:0004160
Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.
2 Q5AZD4 (/RCA) Q5AZD4 (/RCA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 Q9LIR4 (/IDA) Q9LIR4 (/IDA)
Galactonate dehydratase activity GO:0008869
Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O.
2 Q5B2U2 (/RCA) Q5B2U2 (/RCA)
Hydro-lyase activity GO:0016836
Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
2 Q9LIR4 (/TAS) Q9LIR4 (/TAS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q1JUQ1 (/IDA)
L-arabinonate dehydratase activity GO:0050020
Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O.
1 Q1JUQ1 (/IDA)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
D-gluconate catabolic process GO:0046177
The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.
106 P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP) P0ADF6 (/IMP)
(96 more)
Isoleucine biosynthetic process GO:0009097
The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
15 P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA)
(5 more)
Valine biosynthetic process GO:0009099
The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.
15 P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA)
(5 more)
Branched-chain amino acid biosynthetic process GO:0009082
The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
8 P9WKJ5 (/IDA) P9WKJ5 (/IDA) P9WKJ5 (/IDA) P9WKJ5 (/IDA) P9WKJ5 (/IDA) P9WKJ5 (/IDA) P9WKJ5 (/IDA) P9WKJ5 (/IDA)
Branched-chain amino acid biosynthetic process GO:0009082
The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
8 P39522 (/IMP) P39522 (/IMP) P39522 (/IMP) Q4X099 (/IMP) Q4X099 (/IMP) Q4X099 (/IMP) Q9LIR4 (/IMP) Q9LIR4 (/IMP)
Isoleucine biosynthetic process GO:0009097
The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
8 Q10318 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS)
Valine biosynthetic process GO:0009099
The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.
8 Q10318 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS) Q9KVW0 (/ISS)
Branched-chain amino acid biosynthetic process GO:0009082
The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
4 Q5AZD4 (/ISA) Q5AZD4 (/ISA) Q5B2U2 (/ISA) Q5B2U2 (/ISA)
Entner-Doudoroff pathway through 6-phosphogluconate GO:0009255
A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it.
3 Q9KV69 (/ISS) Q9KV69 (/ISS) Q9KV69 (/ISS)
Branched-chain amino acid metabolic process GO:0009081
The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
2 Q5AZD4 (/RCA) Q5AZD4 (/RCA)
Embryo sac development GO:0009553
The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate.
2 Q9LIR4 (/IMP) Q9LIR4 (/IMP)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
2 Q9LIR4 (/IMP) Q9LIR4 (/IMP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 Q9LIR4 (/IMP) Q9LIR4 (/IMP)
Galactonate metabolic process GO:0019583
The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose.
2 Q5B2U2 (/RCA) Q5B2U2 (/RCA)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
2 Q9LIR4 (/IMP) Q9LIR4 (/IMP)
Leucine metabolic process GO:0006551
The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.
1 Q10318 (/ISS)
L-arabinose catabolic process to 2-oxoglutarate GO:0019570
The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate.
1 Q1JUQ1 (/IDA)
Polyketide biosynthetic process GO:0030639
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
1 Q2TXQ3 (/IGC)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
15 P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA) P05791 (/IDA)
(5 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 P9WKJ5 (/HDA) P9WKJ5 (/HDA) P9WKJ5 (/HDA) P9WKJ5 (/HDA) P9WKJ5 (/HDA) P9WKJ5 (/HDA) P9WKJ5 (/HDA) P9WKJ5 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 P39522 (/HDA) P39522 (/HDA) P39522 (/HDA) Q10318 (/HDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q9LIR4 (/IDA) Q9LIR4 (/IDA)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
2 Q9LIR4 (/IDA) Q9LIR4 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
2 Q9LIR4 (/IDA) Q9LIR4 (/IDA)