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CATH Superfamily 3.50.30.40

Ribonuclease E inhibitor RraA/RraA-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease E inhibitor RraA/RraA-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: D-arabino-3-hexulose 6-phosphate formaldehyde lyas...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-hexulose-6-phosphate synthase. [EC: 4.1.2.43]
D-arabino-hex-3-ulose 6-phosphate = D-ribulose 5-phosphate + formaldehyde.
  • Specific for formaldehyde and D-ribulose 5-phosphate as substrates.
  • Ribose 5-phosphate, xylulose 5-phosphate, allulose 6-phosphate and fructose 6-phosphate cannot act as substrate.
  • This enzyme, along with EC 5.3.1.27, plays a key role in the ribulose-monophosphate cycle of formaldehyde fixation, which is present in many microorganisms that are capable of utilizing C1-compounds.
  • The hyperthermophilic and anaerobic archaeon Pyrococcus horikoshii OT3 constitutively produces a bifunctional enzyme that sequentially catalyzes the reactions of this enzyme and EC 5.3.1.27.
 4 A0A0E3LMD0 A0A0E3LMD0 Q46DA4 Q46DA4