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CATH Superfamily 3.50.30.40

Ribonuclease E inhibitor RraA/RraA-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease E inhibitor RraA/RraA-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloace...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
4-hydroxy-4-methyl-2-oxoglutarate aldolase. [EC: 4.1.3.17]
(1) 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate. (2) 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = oxaloacetate + pyruvate.
  • This enzyme participates in the degradation of protocatechuate (via the meta-cleavage pathway), phthalate, syringate and gallate.
  • The enzyme from Pseudomonas ochraceae can also cleave 4-hydroxy-2- oxoglutarate to glyoxylate and pyruvate, and also catalyzes the reaction of EC 4.1.1.3.
 15 A0A1Y1J0W5 A0A1Y1J0W5 A0A1Y1J0W5 A0A2V4FZJ2 A0A2V4FZJ2 D8D902 D8D902 D8D902 G2IQQ8 Q88JX9
(5 more...)
Oxaloacetate decarboxylase. [EC: 4.1.1.112]
Oxaloacetate = pyruvate + CO(2).
  • The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).
  • Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.
  • Formerly EC 4.1.1.3.
 11 A0A1Y1J0W5 A0A1Y1J0W5 A0A1Y1J0W5 D8D902 D8D902 D8D902 G2IQQ8 Q8EE23 Q9AQI0 Q9AQI0
(1 more...)
4-hydroxy-2-oxoglutarate aldolase. [EC: 4.1.3.16]
4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
  • The enzymes from rat liver and bovine liver act on both enantiomers of 4-hydroxy-2-oxoglutarate.
  • Formerly EC 4.1.2.1 and EC 4.1.2.31.
 9 A0A1Y1J0W5 A0A1Y1J0W5 A0A1Y1J0W5 D8D902 D8D902 D8D902 Q9AQI0 Q9AQI0 Q9AQI0