The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Kinesin motor domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 106: Kinesin-like protein KAR3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATP-dependent microtubule motor activity, minus-end-directed GO:0008569
Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP.
8 P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) Q6FVW6 (/IDA) Q6FVW6 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 P17119 (/IPI) P17119 (/IPI) P17119 (/IPI) P17119 (/IPI) P17119 (/IPI) P17119 (/IPI)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
6 P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 A0A1D8PIH0 (/IPI)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Karyogamy involved in conjugation with cellular fusion GO:0000742
During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy.
7 A0A1D8PIH0 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
6 P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP)
Nuclear migration involved in conjugation with cellular fusion GO:0000743
The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion.
6 P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP)
Mitotic sister chromatid cohesion GO:0007064
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
6 P17119 (/IGI) P17119 (/IGI) P17119 (/IGI) P17119 (/IGI) P17119 (/IGI) P17119 (/IGI)
Mitotic sister chromatid cohesion GO:0007064
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
6 P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP)
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
6 P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA)
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
6 P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP)
Regulation of mitotic spindle organization GO:0060236
Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
6 P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP) P17119 (/IMP)
Minus-end directed microtubule sliding GO:0031534
The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.
2 Q6FVW6 (/IDA) Q6FVW6 (/IDA)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
1 A0A1D8PIH0 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 A0A1D8PIH0 (/IMP)
Phenotypic switching GO:0036166
A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.
1 A0A1D8PIH0 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
1 A0A1D8PIH0 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
1 A0A1D8PIH0 (/IMP)
Nuclear membrane fusion involved in karyogamy GO:0048288
The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.
1 A0A1D8PIH0 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
7 A0A1D8PIH0 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA)
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
6 P17119 (/HDA) P17119 (/HDA) P17119 (/HDA) P17119 (/HDA) P17119 (/HDA) P17119 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 P17119 (/HDA) P17119 (/HDA) P17119 (/HDA) P17119 (/HDA) P17119 (/HDA) P17119 (/HDA)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
6 P17119 (/HDA) P17119 (/HDA) P17119 (/HDA) P17119 (/HDA) P17119 (/HDA) P17119 (/HDA)
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
6 P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA) P17119 (/IDA)
Kinesin complex GO:0005871
Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work.
2 Q6FVW6 (/IDA) Q6FVW6 (/IDA)