The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Histone deacetylase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 11: Histone deacetylase HOS3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histone deacetylase activity GO:0004407
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
7 Q02959 (/IDA) Q02959 (/IDA) Q02959 (/IDA) Q02959 (/IDA) Q02959 (/IDA) Q02959 (/IDA) Q02959 (/IDA)
Histone deacetylase activity GO:0004407
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
1 G4N4X5 (/ISS)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
7 Q02959 (/IGI) Q02959 (/IGI) Q02959 (/IGI) Q02959 (/IGI) Q02959 (/IGI) Q02959 (/IGI) Q02959 (/IGI)
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
7 Q02959 (/IPI) Q02959 (/IPI) Q02959 (/IPI) Q02959 (/IPI) Q02959 (/IPI) Q02959 (/IPI) Q02959 (/IPI)
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
7 Q02959 (/IDA) Q02959 (/IDA) Q02959 (/IDA) Q02959 (/IDA) Q02959 (/IDA) Q02959 (/IDA) Q02959 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
7 Q02959 (/IMP) Q02959 (/IMP) Q02959 (/IMP) Q02959 (/IMP) Q02959 (/IMP) Q02959 (/IMP) Q02959 (/IMP)
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
1 G4N4X5 (/ISS)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Prospore membrane GO:0005628
The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.
7 Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
7 Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA) Q02959 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 G4N4X5 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 G4N4X5 (/ISS)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
1 G4N4X5 (/ISS)