The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Peptidoglycan recognition protein-like
".
FunFam 20: Peptidoglycan recognition protein LC, isoform H
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q9GNK5 (/IPI) Q9GNK5 (/IPI) |
|
Signaling pattern recognition receptor activity GO:0008329
Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
|
2 | Q9GNK5 (/TAS) Q9GNK5 (/TAS) |
|
Peptidoglycan receptor activity GO:0016019
Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Peptidoglycan receptor activity GO:0016019
Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity.
|
2 | Q9GNK5 (/TAS) Q9GNK5 (/TAS) |
|
Peptidoglycan binding GO:0042834
Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
|
2 | Q9GNK5 (/IDA) Q9GNK5 (/IDA) |
|
Peptidoglycan binding GO:0042834
Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
|
2 | Q9GNK5 (/ISS) Q9GNK5 (/ISS) |
|
Peptidoglycan binding GO:0042834
Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
|
2 | Q9GNK5 (/TAS) Q9GNK5 (/TAS) |
|
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
2 | Q9GNK5 (/IDA) Q9GNK5 (/IDA) |
|
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
2 | Q9GNK5 (/NAS) Q9GNK5 (/NAS) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of humoral immune response GO:0002920
Any process that modulates the frequency, rate, or extent of a humoral immune response.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
|
2 | Q9GNK5 (/ISS) Q9GNK5 (/ISS) |
|
Positive regulation of antibacterial peptide biosynthetic process GO:0006963
Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Positive regulation of antibacterial peptide biosynthetic process GO:0006963
Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis.
|
2 | Q9GNK5 (/TAS) Q9GNK5 (/TAS) |
|
Positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria GO:0006964
Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Antimicrobial humoral response GO:0019730
An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Antibacterial humoral response GO:0019731
An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Regulation of melanization defense response GO:0035007
Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
2 | Q9GNK5 (/TAS) Q9GNK5 (/TAS) |
|
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
2 | Q9GNK5 (/IDA) Q9GNK5 (/IDA) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
2 | Q9GNK5 (/TAS) Q9GNK5 (/TAS) |
|
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Peptidoglycan recognition protein signaling pathway GO:0061057
A series of molecular signals initiated by binding of peptidoglycan to a receptor on the surface of the target cell and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.
|
2 | Q9GNK5 (/IDA) Q9GNK5 (/IDA) |
|
Peptidoglycan recognition protein signaling pathway GO:0061057
A series of molecular signals initiated by binding of peptidoglycan to a receptor on the surface of the target cell and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.
|
2 | Q9GNK5 (/IGI) Q9GNK5 (/IGI) |
|
Peptidoglycan recognition protein signaling pathway GO:0061057
A series of molecular signals initiated by binding of peptidoglycan to a receptor on the surface of the target cell and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.
|
2 | Q9GNK5 (/IMP) Q9GNK5 (/IMP) |
|
Positive regulation of peptidoglycan recognition protein signaling pathway GO:0061059
Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
|
2 | Q9GNK5 (/IGI) Q9GNK5 (/IGI) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q9GNK5 (/IDA) Q9GNK5 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9GNK5 (/IDA) Q9GNK5 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9GNK5 (/TAS) Q9GNK5 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9GNK5 (/IDA) Q9GNK5 (/IDA) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9GNK5 (/ISS) Q9GNK5 (/ISS) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9GNK5 (/NAS) Q9GNK5 (/NAS) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9GNK5 (/TAS) Q9GNK5 (/TAS) |
|
Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
|
2 | Q9GNK5 (/IDA) Q9GNK5 (/IDA) |
|
Spanning component of plasma membrane GO:0044214
The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
|
2 | Q9GNK5 (/ISM) Q9GNK5 (/ISM) |
|
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
|
2 | Q9GNK5 (/IDA) Q9GNK5 (/IDA) |