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CATH Superfamily 3.40.718.10

Isopropylmalate Dehydrogenase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Isopropylmalate Dehydrogenase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23: Isocitrate dehydrogenase [NADP]

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Isocitrate dehydrogenase (NADP+) activity GO:0004450
Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+.
 15 Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS)
(5 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Isocitrate metabolic process GO:0006102
The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.
 15 Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS) Q8I6T2 (/ISS)
(5 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.