The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldehyde Dehydrogenase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: ALD5p Mitochondrial aldehyde dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aldehyde dehydrogenase (NAD) activity GO:0004029
Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
15 P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P46367 (/IDA) P46367 (/IDA)
(5 more)
Aldehyde dehydrogenase [NAD(P)+] activity GO:0004030
Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.
14 P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P40047 (/IDA) P46367 (/IDA) P46367 (/IDA)
(4 more)
Aldehyde dehydrogenase (NAD) activity GO:0004029
Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
6 P46367 (/IMP) P46367 (/IMP) P46367 (/IMP) P46367 (/IMP) P46367 (/IMP) P46367 (/IMP)
Aldehyde dehydrogenase (NAD) activity GO:0004029
Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
6 Q54FY1 (/ISS) Q54FY2 (/ISS) Q54FY3 (/ISS) Q56YU0 (/ISS) Q8S528 (/ISS) Q9SU63 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q9SU63 (/IDA)
Coniferyl-aldehyde dehydrogenase activity GO:0050269
Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.
1 Q56YU0 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acetate biosynthetic process GO:0019413
The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.
8 P40047 (/IMP) P40047 (/IMP) P40047 (/IMP) P40047 (/IMP) P40047 (/IMP) P40047 (/IMP) P40047 (/IMP) P40047 (/IMP)
Ethanol metabolic process GO:0006067
The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
6 P46367 (/IMP) P46367 (/IMP) P46367 (/IMP) P46367 (/IMP) P46367 (/IMP) P46367 (/IMP)
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
6 P46367 (/IMP) P46367 (/IMP) P46367 (/IMP) P46367 (/IMP) P46367 (/IMP) P46367 (/IMP)
NADPH regeneration GO:0006740
A metabolic process that generates a pool of NADPH by the reduction of NADP+.
6 P46367 (/IGI) P46367 (/IGI) P46367 (/IGI) P46367 (/IGI) P46367 (/IGI) P46367 (/IGI)
Acetate biosynthetic process GO:0019413
The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.
6 P46367 (/IGI) P46367 (/IGI) P46367 (/IGI) P46367 (/IGI) P46367 (/IGI) P46367 (/IGI)
Phenylpropanoid biosynthetic process GO:0009699
The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid.
1 Q56YU0 (/IDA)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 Q9SU63 (/IEP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
14 P40047 (/HDA) P40047 (/HDA) P40047 (/HDA) P40047 (/HDA) P40047 (/HDA) P40047 (/HDA) P40047 (/HDA) P40047 (/HDA) P46367 (/HDA) P46367 (/HDA)
(4 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
7 P46367 (/IDA) P46367 (/IDA) P46367 (/IDA) P46367 (/IDA) P46367 (/IDA) P46367 (/IDA) Q9SU63 (/IDA)
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
6 P46367 (/IDA) P46367 (/IDA) P46367 (/IDA) P46367 (/IDA) P46367 (/IDA) P46367 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q9SU63 (/IDA)