The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CRAL-TRIO lipid binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 9: SEC14-like 2 (S. cerevisiae)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2 O76054 (/NAS) O76054 (/NAS)
Vitamin E binding GO:0008431
Interacting selectively and non-covalently with vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
2 O76054 (/NAS) O76054 (/NAS)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 A2BIR0 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 A2BIR0 (/IPI)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
1 A2BIR0 (/IDA)
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
1 Q99MS0 (/IDA)
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
1 Q99J08 (/ISO)
Transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765
Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).
1 Q99MS0 (/IDA)
Transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765
Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).
1 Q99J08 (/ISO)
GTPase activating protein binding GO:0032794
Interacting selectively and non-covalently with a GTPase activating protein.
1 A2BIR0 (/IPI)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of cholesterol biosynthetic process GO:0045540
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
2 O76054 (/NAS) O76054 (/NAS)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 O76054 (/NAS) O76054 (/NAS)
Wnt signaling pathway, calcium modulating pathway GO:0007223
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
1 A2BIR0 (/IGI)
Wnt signaling pathway, calcium modulating pathway GO:0007223
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
1 A2BIR0 (/IMP)
Positive regulation of cholesterol biosynthetic process GO:0045542
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
1 Q99MS0 (/IDA)
Positive regulation of cholesterol biosynthetic process GO:0045542
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
1 Q99J08 (/ISO)
Regulation of convergent extension involved in axis elongation GO:1901232
Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation.
1 A2BIR0 (/IGI)
Regulation of convergent extension involved in axis elongation GO:1901232
Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation.
1 A2BIR0 (/IMP)
Positive regulation of epiboly involved in gastrulation with mouth forming second GO:1904088
Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.
1 A2BIR0 (/IGI)
Positive regulation of epiboly involved in gastrulation with mouth forming second GO:1904088
Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.
1 A2BIR0 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 A0A024R1I5 (/IDA) A0A024R1I5 (/IDA) B3KRD8 (/IDA) C9JZI9 (/IDA) O76054 (/IDA) O76054 (/IDA) Q99MS0 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 A0A024R1I5 (/IDA) A0A024R1I5 (/IDA) B3KRD8 (/IDA) C9JZI9 (/IDA) O76054 (/IDA) O76054 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
3 O76054 (/HDA) O76054 (/HDA) Q9UDX4 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O76054 (/NAS) O76054 (/NAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 O76054 (/NAS) O76054 (/NAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q99J08 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q99J08 (/ISO)
Extrinsic component of plasma membrane GO:0019897
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 A2BIR0 (/IDA)