The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CRAL-TRIO lipid binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: Phosphatidylinositol transfer protein PDR16

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphatidylinositol transfer activity GO:0008526
Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
13 P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53860 (/IDA) P53860 (/IDA) P53860 (/IDA)
(3 more)
Phosphatidylinositol transfer activity GO:0008526
Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
13 P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53860 (/IGI) P53860 (/IGI) P53860 (/IGI)
(3 more)
Phosphatidylinositol transfer activity GO:0008526
Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
13 P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53860 (/IMP) P53860 (/IMP) P53860 (/IMP)
(3 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 P53844 (/IPI) P53844 (/IPI) P53844 (/IPI) P53844 (/IPI) P53844 (/IPI) P53844 (/IPI) P53844 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
6 P53860 (/IPI) P53860 (/IPI) P53860 (/IPI) P53860 (/IPI) P53860 (/IPI) P53860 (/IPI)
Phosphatidylinositol transfer activity GO:0008526
Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
1 A0A1D8PD50 (/NAS)
Phospholipid transfer activity GO:0120014
Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
1 Q9UU99 (/ISM)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phospholipid biosynthetic process GO:0008654
The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
13 P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53860 (/IGI) P53860 (/IGI) P53860 (/IGI)
(3 more)
Phospholipid transport GO:0015914
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
13 P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53860 (/IDA) P53860 (/IDA) P53860 (/IDA)
(3 more)
Phospholipid transport GO:0015914
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
13 P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53860 (/IGI) P53860 (/IGI) P53860 (/IGI)
(3 more)
Phospholipid transport GO:0015914
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
13 P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53860 (/IMP) P53860 (/IMP) P53860 (/IMP)
(3 more)
Sterol biosynthetic process GO:0016126
The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
13 P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53860 (/IGI) P53860 (/IGI) P53860 (/IGI)
(3 more)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
13 P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53860 (/IGI) P53860 (/IGI) P53860 (/IGI)
(3 more)
Phosphatidylserine metabolic process GO:0006658
The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes.
7 P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP) P53844 (/IMP)
Golgi to plasma membrane protein transport GO:0043001
The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
7 P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI)
Negative regulation of phosphatidylglycerol biosynthetic process GO:1901352
Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process.
7 P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI)
Positive regulation of phosphatidylcholine biosynthetic process GO:2001247
Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process.
7 P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI) P53844 (/IGI)
Negative regulation of sexual sporulation resulting in formation of a cellular spore GO:0043942
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
6 P53860 (/IMP) P53860 (/IMP) P53860 (/IMP) P53860 (/IMP) P53860 (/IMP) P53860 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 A0A1D8PD50 (/IMP) A0A1D8PGP3 (/IMP)
Intermembrane phospholipid transfer GO:0120010
The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane.
1 Q9UU99 (/ISM)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
13 P53844 (/HDA) P53844 (/HDA) P53844 (/HDA) P53844 (/HDA) P53844 (/HDA) P53844 (/HDA) P53844 (/HDA) P53860 (/HDA) P53860 (/HDA) P53860 (/HDA)
(3 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
13 P53844 (/HDA) P53844 (/HDA) P53844 (/HDA) P53844 (/HDA) P53844 (/HDA) P53844 (/HDA) P53844 (/HDA) P53860 (/HDA) P53860 (/HDA) P53860 (/HDA)
(3 more)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
13 P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53860 (/IDA) P53860 (/IDA) P53860 (/IDA)
(3 more)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
7 P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA) P53844 (/IDA)
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
6 P53860 (/IDA) P53860 (/IDA) P53860 (/IDA) P53860 (/IDA) P53860 (/IDA) P53860 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 P53860 (/HDA) P53860 (/HDA) P53860 (/HDA) P53860 (/HDA) P53860 (/HDA) P53860 (/HDA)
Nucleus-vacuole junction GO:0071561
An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.
6 P53860 (/IDA) P53860 (/IDA) P53860 (/IDA) P53860 (/IDA) P53860 (/IDA) P53860 (/IDA)
Prospore membrane GO:0005628
The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.
1 Q9UU99 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9UU99 (/IDA)