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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 607: Inositol-3-phosphate synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
 12 Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA)
(2 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Inositol biosynthetic process GO:0006021
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
 12 Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA) Q8I3Y8 (/IDA)
(2 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.