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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 59: L-threonine 3-dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ferrous iron binding GO:0008198
Interacting selectively and non-covalently with ferrous iron, Fe(II).
 12 P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA)
(2 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
 12 P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA)
(2 more)
L-threonine 3-dehydrogenase activity GO:0008743
Catalysis of the reaction: L-threonine + NAD(+) = aminoacetone + CO(2) + NADH.
 12 P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA)
(2 more)
Oxidoreductase activity GO:0016491
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
 12 P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA)
(2 more)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
 12 P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA)
(2 more)
Cadmium ion binding GO:0046870
Interacting selectively and non-covalently with cadmium (Cd) ions.
 12 P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA)
(2 more)
L-threonine 3-dehydrogenase activity GO:0008743
Catalysis of the reaction: L-threonine + NAD(+) = aminoacetone + CO(2) + NADH.
 8 Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
L-serine biosynthetic process GO:0006564
The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
 12 P07913 (/IGI) P07913 (/IGI) P07913 (/IGI) P07913 (/IGI) P07913 (/IGI) P07913 (/IGI) P07913 (/IGI) P07913 (/IGI) P07913 (/IGI) P07913 (/IGI)
(2 more)
Threonine catabolic process GO:0006567
The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
 12 P07913 (/IMP) P07913 (/IMP) P07913 (/IMP) P07913 (/IMP) P07913 (/IMP) P07913 (/IMP) P07913 (/IMP) P07913 (/IMP) P07913 (/IMP) P07913 (/IMP)
(2 more)
Threonine catabolic process GO:0006567
The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
 8 Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS) Q9KL62 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 12 P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 12 P07913 (/HDA) P07913 (/HDA) P07913 (/HDA) P07913 (/HDA) P07913 (/HDA) P07913 (/HDA) P07913 (/HDA) P07913 (/HDA) P07913 (/HDA) P07913 (/HDA)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 12 P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA) P07913 (/IDA)
(2 more)