The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 588: Putative ubiquitin activating enzyme
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | Q99344 (/IPI) Q99344 (/IPI) Q99344 (/IPI) Q99344 (/IPI) Q99344 (/IPI) |
|
NEDD8 activating enzyme activity GO:0019781
Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.
|
5 | Q99344 (/IDA) Q99344 (/IDA) Q99344 (/IDA) Q99344 (/IDA) Q99344 (/IDA) |
|
Ubiquitin activating enzyme activity GO:0004839
Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.
|
1 | Q38F81 (/ISM) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein neddylation GO:0045116
Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.
|
5 | Q99344 (/IDA) Q99344 (/IDA) Q99344 (/IDA) Q99344 (/IDA) Q99344 (/IDA) |
|
Protein neddylation GO:0045116
Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.
|
5 | Q99344 (/IMP) Q99344 (/IMP) Q99344 (/IMP) Q99344 (/IMP) Q99344 (/IMP) |
|
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
|
1 | Q38F81 (/ISM) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | Q99344 (/HDA) Q99344 (/HDA) Q99344 (/HDA) Q99344 (/HDA) Q99344 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q38F81 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q38F81 (/ISM) |