The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 467: Steroid dehydrogenase 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Testosterone dehydrogenase [NAD(P)] activity GO:0030283
Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+.
|
2 | C1P622 (/IDA) Q09517 (/IDA) |
|
Long-chain-fatty-acyl-CoA reductase activity GO:0050062
Catalysis of the reaction: a long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH.
|
2 | C1P622 (/IDA) Q09517 (/IDA) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Steroid biosynthetic process GO:0006694
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
|
2 | C1P622 (/IDA) Q09517 (/IDA) |
|
Androgen metabolic process GO:0008209
The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
|
2 | C1P622 (/IMP) Q09517 (/IMP) |
|
Estrogen metabolic process GO:0008210
The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
|
2 | C1P622 (/IMP) Q09517 (/IMP) |
|
Molting cycle, collagen and cuticulin-based cuticle GO:0018996
The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans.
|
2 | C1P622 (/IMP) Q09517 (/IMP) |
|
Long-chain fatty acid biosynthetic process GO:0042759
The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.
|
2 | C1P622 (/IDA) Q09517 (/IDA) |
|
Reproduction GO:0000003
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
|
1 | Q09517 (/IMP) |
|
Reproduction GO:0000003
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
|
1 | Q60V51 (/ISS) |
|
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
1 | Q09517 (/IMP) |
|
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
1 | Q60V51 (/ISS) |
|
Female genitalia development GO:0030540
The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure.
|
1 | Q09517 (/IMP) |
|
Female genitalia development GO:0030540
The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure.
|
1 | Q60V51 (/ISS) |
|
Regulation of hormone metabolic process GO:0032350
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
|
1 | Q09517 (/IMP) |
|
Regulation of hormone metabolic process GO:0032350
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
|
1 | Q60V51 (/ISS) |
|
Molting cycle GO:0042303
The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc.
|
1 | Q09517 (/IMP) |
|
Molting cycle GO:0042303
The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc.
|
1 | Q60V51 (/ISS) |
|
Establishment or maintenance of epithelial cell apical/basal polarity GO:0045197
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
|
1 | Q09517 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | C1P622 (/IDA) Q09517 (/IDA) |
|
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
|
2 | C1P622 (/IDA) Q09517 (/IDA) |